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We have studied the oxidative metabolism of CLZ and OLZ as well as two known metabolites of CLZ, desmethyl-CLZ (DCLZ), and CLZ-N-oxide (CLZ-NO), using in vitro rat liver microsomal (RLM) incubations with glutathione (GSH) trapping of reactive metabolites and liquid chromatography-high resolution tandem mass spectrometry (LC-HRMS/MS)

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Optimal batch fermentation was established at 20 C and pH 4.5 using a cost-effective medium of molasses and corn steep liquor (CSL)

Available evidence suggests that PRP and PRGF supplementation in culture media may enhance in vitro sperm generation by improving cell viability and proliferation