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The main pathological hallmark of Parkinsons disease is the accumulation of Lewy bodies, whose main protein component is -synuclein (-syn) [7]

Recent trends and advances of RNA interference (RNAi) to improve agricultural crops and enhance their resilience to biotic and abiotic stresses

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TCMs and NPs provide a huge source for the research and discovery of new drugs by virtue of their obvious anti-inflammatory, antioxidant, liver protective and other effects and have attracted widespread attention

Recombinant human BDNF and ANA-12 (Sigma-Aldrich) was incubated during 24h at 1 nM and 50 M, respectively

For cultured astrocytes, the processes that are mainly responsible for the consumption of intracellular GSH aredepending on the experimental conditions appliedthe oxidation of GSH to GSSG by GPx, the conjugation of GSH with electrophiles, and/or the export of GSH, GSSG, and GSHconjugates (Figure 2)