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Description
The cyclic form is the product of nucleophilic attack by the oxygen of a hydroxyl group on the electrophilic carbon of the carbonyl group within the same molecule, producing a stable ring structure composed of five or six carbons that minimizes bond strain (Figure 24.21 "Fischer Projection and Haworth Projection of Glucose")

85 In 2011, the FDA approved vemurafenib for BRAFV600E/K+ patients earning MM, a mention as the poster child for personalized medicine

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In rare cases, it can develop in other parts of the body

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