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In times of metabolic sufficiency, fatty acids are used to synthesize TG and enhance adipose tissues storage

Furthermore, ferroptosis is related not only to NETs but also to autoimmune diseases associated with neutrophils

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Andreeff M , Goodacre AM, Pereira-Leahy JM, Reading C, Deisseroth A

These findings underscore OS as a central mediator of -cell failure in diabetes, highlighting the need for targeted antioxidant strategies (see Figure 3) that mitigate ROS without disrupting physiological redox signaling (Zaher and Stephens, 2025)