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In contrast to serum IGF-1, IGF-1R activity, especially cytoplasmic and nuclear IGF-1R expression, has been proven to promote radiotherapy resistance and enhance the risk of biological cancer recurrence [41]

2022;17:e0269440

The biosynthetic pathway in question is restricted to specific microbes and archaea

5, 1 May 2014, pp

Finally, an immunological exhaustion of T cells (PD-1+/Tim-3+) is produced by chronic exposure to viral antigens, with consolidation of the disease (135, 136)

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