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28 NakamuraT.Abe-KanohN.NakamuraY

Many practitioners recommend supplementing iodine for hypothyroid patients, sometimes in very high doses, because the thyroid hormone molecule is made up partly of iodine

doi: 10.1002/mrm.1094

Dalton Transactions, (21), 21122114

Annu Rev Biochem 52, 711760, doi: 10.1146/annurev.bi.52.070183.003431 (1983)

Indeed, silencing -syn has led to neuroprotection in vitro upon 1-methyl-4-phenylpyridinium (MPP+) insult (Fountaine and Wade-Martins, via a lentiviral vector silenced human -syn expression in rat striatum, and siRNA directed against -syn reduced the expression of endogenous -syn after 2 weeks of infusion into the mouse hippocampus (Sapru et al., In addition to targeting -syn mRNA translation processes, an alternative approach to reduce -syn protein expression seeks to interfere with the transcription of the -syn gene
