antioxidants glutathione Treatments 101: Part 1 — The Mother of All The Super Antioxidants: Glutathione And
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[Abstract]2026 Mar 17;7(3):102635

doi: 10.1126/science.177.4046.314 61 OkamotoTIsodaHKubotaNTakahataKTakahashiTKishiTet al
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Levine RL, Mosoni L, Berlett BS, Stadtman ER

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The enhanced proliferative response of vascular smooth muscle cells was shown to be caused by the inactivation of the SH2 domain-containing protein tyrosine phosphatase 2 (SHP-2 phosphatase) by glutathionylation to allow for the sustained phosphorylation and activation of the tyrosine kinase ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase)

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