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SAM-e is the bodys primary methyl donor, providing direct and immediate methylation support without requiring metabolic conversion

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Errors occur when researchers dont account for actual reconstitution volume or use syringes without clear unit markings

Animals were anaesthetized with ethyl ether after which a single intracolonic dose of 30 mg of TNBS dissolved in 0.25 ml of either 50% ethanol in saline (v/v) or saline, referred as TNBS+ethanol or TNBS+saline, respectively, was administered

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This hypothetical mechanism also must be confirmed by experiments
