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We detected an increase in IFN- producers and triple IFN-/TNF/IL-2 producers (Figure 7, I and J, and Supplemental Figure 7D) in CMV-specific CD8 + T cells from noncontrollers, whereas no effects were observed in controllers

Together, PRX3 deletion in H-MESO-1 cells inhibits tumor growth properties and elicits significant changes to the redox and metabolic status of mitochondria

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Metabolitegene interaction analysis further identified several genes functionally linked to the observed metabolic network (Fig