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In response to oxidative stress, cellular GSH levels decrease significantly, and the oxidized derivatives of this molecule increase (Wu et al., 2004)

doi: 10.1016/j.carbpol.2022.119273

doi: 10.1016/j.bmcl.2012.04.081

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N-acetylcysteine has a high safety profile, and the studies do not report any major or serious adverse effect of NAC

Uzawa A, Suzuki S, Kuwabara S, Akamine H, Onishi Y, Yasuda M, et al