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Efforts have been made to target serine metabolism, with a specific focus on phosphoglycerate dehydrogenase (PHGDH), a rate-limiting enzyme in the serine de novo synthesis pathway 38,151,152,153

After multiple doses, IGF-1 levels remained elevated above baseline for up to 28 days

Boosts antioxidant activity

But according to the metal cofactors at their active sites, SODs can also be divided into four different types: Nickel SOD (Ni-SOD), manganese SOD (Mn-SOD), iron SOD (Fe-SOD) and copperZinc SOD (Cu,Zn-SOD) [14]
