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Description
Studies have shown that IL-17A downregulates the expression of downstream target genes in the Wnt/-catenin signalling pathway, such as AXIN2 and CCND1, in osteoblasts and osteocytes, leading to bone loss by inhibiting the activity of osteoblasts and osteocytes
An example of an autoimmune disease that may be treated with cell-based therapy is multiple sclerosis, which shares some similarities with ALS
Jackson et al., 2022)
Drugs for other psychiatric conditions (e.g
Treatment with rapamycin reverses this process by downregulating YY1 expression
SN Appl Sci 3:19
