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Figure 3 Anorexia nervosa is a condition of severe undernutrition characterized by GH resistance secondary to chronic nutritional deprivation with resultant high GH and low serum levels of free, bioactive and total IGF-I (56)

It differs from the morphological characteristics of typical necrosis and does not exhibit features such as rupture of the plasma membrane, cytoplasmic swelling, and moderate chromatin condensation

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Specifically, TMA moieties (such as choline, phosphatidylcholine, and L-carnitine) containing fatty acids are converted to TMA by bacterial TMA lyase via various metabolic pathways (235)

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Additionally, proprioceptive training can modulate neurotransmitter systems involved in sensory-motor integration