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Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts
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The block of the GCLC enzyme may explain the decrease of GSH previously found in OTA-treated cell cultures [29]
Recently, a potato ( S
78 , 171 (1970) Boivin, P., Galand, C., Bernard, J.: Deficiencies in GSH biosynthesis
however, there has been a gradual increase in the incidence of this disease among children and adolescents in recent times [105, 106]
