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Patients who have been newly or recently diagnosed with Graves disease typically exhibit low levels of selenium and produce thyroid-stimulating immunoglobulin, which leads to the overproduction of thyroid hormones [27]

Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy

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7 Conclusions and future directions Many environmental factors can influence the development of the thyroid gland and its function throughout life, and there is a need for monitoring and further understanding

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