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Joseph et al., 2011) and increased excitotoxicity (Rzheshevsky, 2014) (Figure 3)

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(2023) framed QS inhibition as a physicochemically informed anti-virulence strategy: small lipophilic phytophenols (e.g., eugenol) can perturb membrane microdomains and disrupt signal transduction or ligandreceptor interactions at the cell surface, thereby reducing QS signaling amplitude and downstream virulence gene expression

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