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however, a number of studies reported no improvement [126, 128] and refs therein

Supplements work best when the fundamentals are already in place

The link between the acyl composition of cardiolipin and CAC lies in the fact that this special lipid is essential for the transport activity of CAC (Tonazzi et al., 2015)

l-carnitine was shown to increase gene expression in the liver related to fatty acid transport, -oxidation, and antioxidant enzymes [70]

Raw data for statistical analyses and supplemental data are available at Zenodo (DOI: 10.5281/zenodo.14916225) Ethics statement The animal study was approved by Lower Saxony State Office for Consumer Protection and Food Safety (LAVES, Oldenburg, Germany)

In general, many researchers believe PQQ is safe