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Oral Protocols: Daily oral doses of 1, 5, 10, 20, and 30 mg were evaluated over 12 weeks

The PS for adjustment of toxicities was composed using body surface area, age, histology, relapse after surgical resection, ECOG-PS, comorbidities, chemotherapy line, reduced dosage requirement status, and duration of premedication as independent variables, and the C-statistic of the ROC curve analysis was 0.808

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