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Description
Such findings suggest a possible relationship between the use of antidepressant drugs and their effects on oxidative stress

The ER and the mitochondrial network, although not connected to each other by secretory pathway traffic, are intertwined both physically and functionally

(May 2007)

Thus, xCT inhibitors enhance mitochondrial respiration and increase ROS production to promote ferroptosis, which may be a potential therapeutic strategy in cancer cells exhibiting metabolic reprogramming from glycolysis to OXPHOS

The 3 guidelines (19-21) were assessed using the Appraisal of Guidelines for Research and Evaluation tool

Usage For use only under medical supervision by qualified healthcare professionals
