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The evolution of metalliform diversity can likely be explained by changes in heavy metal bioavailability that took place during large compositional changes of the earth's early atmosphere and oceans

Paz-Alberto A (2013) Phytoremediation: a green technology to remove environmental pollutants

Mechanically, ARID1A is a component of the SWI/SNF complex, which binds to the SLC7A11 promoter and promotes NRF2-mediated SLC7A11 transcriptional activation