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Among them, the large protein ATG2 (~2000 amino acids) containing the Chorein_N-domian plays a critical role in connecting the ER and phagophores by localizing to their contact sites (Gmez-Snchez et al, 2018

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Mechanical breaking of microtubules in axons during dynamic stretch injury underlies delayed elasticity, microtubule disassembly and axon degeneration

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Then loss of appetite, sweating, extreme tiredness, unusual bleeding and pain in the upper right part of stomach may arise, followed by jaundice, confusion and loss of consciousness due to the deterioration of liver function