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Thus, pharmacological strategies that aim to restore balance between IRE1s XBP1s and RIDD activities are not only limited to anticancer therapies but can also be crucial for effective treatments of metabolic disorders such as diabetes
doi: 10.1248/bpb.b17-00855 38 NakaseIGallisBTakatani-NakaseTOhSLacosteESinghNPet al
doi: 10.1016/j.jhep.2007.04.002 Banerjee M, and Saxena M ( 2012 )

Lipidomic results suggest that phosphatidylethanolamine (PE) containing arachidonic acid (AA) is the key membrane phospholipid for the occurrence of oxidation-driven ferroptosis (31)

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