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Am J Pathol 1983;113:198206

Identification of the three zinc-binding sites on tau protein

Most heavy metals are able to efficiently penetrate the bloodbrain barrier and they easily substitute calcium ions during their passage through the bloodbrain barrier, thus interfering with the regulatory action of calcium on brain cells and disrupting the related intracellular activities

In this and several subsequent studies, Ueda et al

The agency's final action follows, typically within a year of the PCAC vote

Neurotoxic effects of triclosan in adolescent mice: pyruvate kinase M2 dimer regulated Signal transducer and activator of transcription 3 phosphorylation mediated microglia activation and neuroinflammation