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CAFs upregulate glycolysis-related enzymes, such as HK2 and 6-phosphofructokinase liver type (PFKL), which is thought to occur via signaling with plateletderived growth factor and transforming growth factor (TGF-) [83]

Nanoxidil is a compound similar to minoxidil and is widely used in hair growth products

Knockdown in murine mesenchymal stem cells and PCG1- null-mouse neurons blunts proper SOD enzyme expression (already reduced in FRDA), consistent with findings of PCG1- downregulation in FRDA fibroblasts (Jiralerspong et al., 2001

Controlled studies for treatments that address mitochondrial disorders include l-carnitine and a multivitamin with various mitochondrial supplements

Crit Rev Food Sci Nutr 62(28):77307742 Rudrapal M, Rakshit G, Singh RP, Garse S, Khan J, Chakraborty S (2024) Dietary polyphenols: review on chemistry/sources, bioavailability/metabolism, antioxidant effects, and their role in disease management

Could Ozempic help your patients who have T2D and CVD