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Schapira AH, Olanow CW (2004) Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions

Brain 132 , 172184 (2009)

Among individuals with CSF and plasma data, AD cases corresponded to those with a diagnosis of dementia of the Alzheimers type (DAT) using criteria equivalent to the National Institute of Neurological and Communication Disorders and Stroke-Alzheimers Disease and Related Disorders Association for probable AD 58 , and AD severity was determined using the Clinical Dementia Rating (CDR) 59 at the time of lumbar puncture (for CSF samples) or blood draw (for plasma samples)

1 C and E ) but not amplitude, consistent with it being a presynaptic precursor of glutamate

However, because it supports detoxification, it may indirectly improve overall cellular balance without acting as a hormonal treatment

JAMA 301 , 6373 (2009)