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Among all the PARPs, only PARP1, PARP2 and PARP3 localize to the nucleus (FIG

The laboratory data demonstrated a normal folic acid level with a low vitamin B12 level

This makes oral supplements less effective for individuals with: Pernicious Anemia: An autoimmune condition where the body can't produce intrinsic factor

NNMT is upregulated in adipose tissue in obesity, and its inhibition is studied as a potential strategy to modulate NAD+ metabolism and metabolic gene expression

Rayyan software (Ouzzani et al., 2016) was employed for reference management, including the identification and removal of duplicate entries
Inadequate levels of B12 can lead to conditions like megaloblastic or pernicious anemia, resulting in fatigue, weakness, and pale skin
