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The specific H3K27 methyltransferase enhancer of zeste homolog 2 (EZH2) confers chemoresistance on ovarian cancer cells through H3K27 methylation [169]

Selenium compounds were able to activate DNA damage response-associated kinases and caused senescence in human embryonic lung fibroblasts cell 5 (MRC-5), but not in human colorectal cell 116 (HCT-116) and prostate cancer cells 3 (PC-3) (163)

Pigmentation, dullness and uneven tone often involve inflammation, sun exposure, barrier disruption and slowed renewal
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