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Acute kidney injury associated with semaglutide

Past clinical studies have shown users of the medications can lose between 5% and 20% of their body weight on the medications over time

These drugs mimic a natural gut hormone (GLP-1) that stimulates insulin secretion, slows digestion, and reduces appetite

Access is tightly limited: enrollees need high BMI scores and certain health conditions, while patients using GLP-1s for diabetes or sleep apnea are excluded and must navigate prescriptions and prior authorizations

Most GLP-1 receptor agonists are administered via subcutaneous injection, with dosing frequencies ranging from daily to once weekly depending on the specific agent