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The World Anti-Doping Agency (WADA) has listed it under S0 Unapproved Substances due to its potential performance-enhancing effects

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Such findings suggest that IGF-1 implications on metabolism may not only affect energy use and balance, but as well act regulating transport and nutrient absorption

Chini EN, Chini CCS, Espindola Netto JM, de Oliveira GC, van Schooten W

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Glutamate and some of its receptors are also involved in neurogenesis and proliferation [92]