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The FabX FMN cofactor is held at an appropriate place inside the active pocket by hydrophilic interactions with the sidechains of N99, E175, Q240, and T243, and the backbones of G25, G180, G221, A242, and T243, as well as hydrophobic interactions with G22, G23, M24, I28, L101, I147, E175, S179, G220, M241, F339, T340, and G341 (Fig

Expression of a catalytically inactive mutant form of glutathione peroxidase 4 (gpx4) confers a dominant-negative effect in male fertility

GLP-1 therapy carries a risk of hypoglycemia (low blood sugar), particularly when used with other diabetes medications that lower blood glucose

(PubMed) Smith AR, Hagen TM

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