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Thus, folate builds up in the form of 5mTHF (the "methyl trap") and there is less folate in the forms CH 2 -THF and 10f-THF that are the substrates for thymidylate and purine synthesis, respectively

Specifically, the human GPx-1 gene has two oxygen response elements (OREs) that, under normoxic conditions, are important for transcription (78)

This direct access allows glutathione to work immediately, neutralizing free radicals and supporting detoxification

More information about sampling is in the article Skiba et al

doi: 10.1007/s00018-016-2190-5