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CL316,243 treatment leads to a 10-fold increase in cardiolipin levels in gWAT and a 2.5-fold increase in iWAT, with 72:8 (18:2) and 72:7 (18:2) showing the most prominent changes 65

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Largest effects were observed in monotherapy vs placebo/no treatment , while head-to-head comparisons did not demonstrate superiority of ALC over antidepressant drugs

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