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Receptoraktivering hjer intracellulrt cAMP och uppregulerar MITF och tyrosinas, vilket driver eumelaninsyntes den signalvg som ligger till grund fr forskning om pigmentering och fotoskydd

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doi: 10.1073/pnas.93.1.131

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This is because the cells that produce the pigment (melanocytes) are located in the nail matrix, which as you can see in the following image, is the most proximal area of the nail

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The significance of microsurgical varicocelectomy in the treatment of subclinical varicocele

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