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Moreover, CD38 deficiency-mediated inhibition of the biogenesis, secretion, and internalization of SA-sEVs by senescent VSMCs was partially involved in reestablishing the function of the mitochondrial-lysosomal axis in smooth muscle cells

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Nasal delivery lets peptides reach the brain more directly through the olfactory pathway

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the standard route for this molecule is oral

Considering that the vessels involved are those of the epineurium and perineurium, MM is usually associated with small to medium vessel vasculitides