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En cas de carence en B12 mais avec un apport suffisant en vitamine B9, il peut ne pas y avoir de mgaloblastose (car on contourne ainsi le pige des folates), ce qui complique son diagnostic
Brooke K
Clinical trials at doses up to 40mg daily for 12 weeks have reported no serious adverse effects (Brendler & Williamson, 2019, Phytomedicine )
Pregnant women need to consume more B12 each day, and should get at least 2.6 micrograms
This may be considered the main effect
The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling
