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doi:10.1212/wnl.57.8.1515 22 Chan, A., Paskavitz, J., Remington, R., Rasmussen, S

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Clinically relevant interactions of anti-Apoptotic BCL-2 protein inhibitors with ABC transporters

R152 and active site residues C46, K48, Q81, and W136 are highlighted and shown as sticks
This result is likely due to the high levels of glutamic acid and glycine, precursors of glutathione, present in CSL (Lusby et al., 1982)