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the later dosing and titration sections explain why response and tolerability matter more than advancing on a fixed calendar

This is due to low absorption in the intestine, and breakdown by enzyme activity

Soni strongly cautions against using any hCG product without a genuine medical need confirmed through blood work
Blood pressure changes were not observed in clinical trials

The safety data is encouraging: no serious adverse events documented across 100+ preclinical studies, no organ damage, and no deaths even at doses 1,000 times typical use (Sikiric et al., 2014

If you notice a significant end-of-week dip in appetite control, it does not necessarily mean you need a higher dose