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Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms

Use insulin syringes (29 to 31 gauge) for comfortable injections

Repair: This is where BPC-157 shines

helps regulate appetite and mood (key factors in overeating), and is a great treatment for people who cannot absorb vitamin B12

Increase to 500mcg if needed after 1-2 weeks