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Another possible therapeutic in development is phenylbutyrate, a drug that lowers glutamine concentrations in the plasma

D.et al (2008)

Modulation of the fumarases of Escherichia coli in response to oxidative stress
Korkushko OV, Khavinson VK, Shatilo VB, et al

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Due to the significant exposure to numerous therapeutic as well as environmental toxicants, kidneys are overwhelmed by several major or minor disorders like acute kidney injury (AKI) and chronic kidney disease (CKD)