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doi: 10.1016/j.ghir.2008.09.002 91 NassRLiuJPezzoliSOliveriMGaylinnBThornerM

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Pyrroloquinoline quinone (PQQ) activates the PGC-1 pathway, restoring mitochondrial function, reducing MuRF1 expression, and alleviating TNF-induced muscle atrophy (Yt et al., 2015)

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It was originally designed as a potential investigational treatment for neurodegenerative conditions, particularly Alzheimers disease

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