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As gene therapy technologies mature, innovations such as genome editing and AI-driven patient identification could further transform clinical development in rare diseases

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The neural pathway from the PVH neurons to the pineal gland is circuitous passing through the spinal cord and superior cervical ganglion (see Fig

This two-step process immunoassay screen plus GC/MS or LC/MS confirmation greatly reduces the chance of a false positive, because the second test is highly accurate and specific to the substance