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In vivo and in vitro experiments have revealed that TMAO increases thrombotic potential by strengthening aortic vascular tissue factor (TF) and vascular cell adhesion molecule (VCAM)1 expression (50)

Goldstein, S., Kukkonen, T., Monsef, A., & Goldstein, I

As the parameters measured did not differ significantly between the two LC doses used, the study concluded that a low dose of LC was sufficient to render positive effects on pregnancy and offspring outcomes in pregnant mice [42]

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