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Bioanalysis of plasma and urine samples Plasma and urine samples were processed using liquidliquid extraction as described

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2 Angiogenesis mechanism of gastric cancer The occurrence and development of tumors depend on angiogenesis, and new blood vessels promote tumor invasion and metastasis ( The VEGF family includes vascular endothelial growth factor A (VEGF-A), vascular endothelial growth factor B (VEGF-B), vascular endothelial growth factor C (VEGF-C), vascular endothelial growth factor D (VEGF-D), vascular endothelial growth factor E (VEGF-E) and placental growth factor (PIGF), whose receptors include 3 tyrosine kinase receptors vascular endothelial growth factor receptor 1 (VEGFR-1, also known as Flt-1), vascular endothelial growth factor receptor 2 (VEGFR-2, also known as KDR/Flk-1), vascular endothelial growth factor receptor 3 (VEGFR-3, also known as Flt-4), whose receptors bind to VEGF with high affinity ( VEGF receptors are transmembrane tyrosine kinases that activate various angiogenic pathways upon ligand binding and receptor dimerization (31)

10.1111/apt.15195 73

BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice