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The recent discovery that histone demethylases KDM5A and KDM6A (also known as UTX) can sense oxygen concentrations and thereby modulate H3K4me3 and H3K27me3 levels 91,92 is a first step in this direction
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The normal balance of immune cells is upset by hyperandrogenism which causes chronic inflammation by stimulating certain immune cells while suppressing others
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The World Health Organization has found populations at heightened risk for diabetes (Han et al., 2019)
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
