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They are composed of a ligand binding domain that interacts with a DNA binding domain to modulate it [130]
This is something that most single peptides cannot do
Complex I stability is determined by CoQ redox state (Guaras et al., 2016) and the reduced form of CoQ (CoQH 2 ) directs complex I-specific ROS production to extend lifespan in Drosophila (Scialo et al., 2016)
doi: 10.15258/sst.2010.38.1.04 28 ChenX.-J.YinY.-Q.ZhuX.-M.XiaX.HanJ.-J
Similarly, probiotics have been demonstrated to have pro-apoptotic and anti-proliferative activities against gastrointestinal cancer with colonic cancer cells and gastric cancer cells being the most frequently researched
(2019) 39:BSR20190867
