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The strong protic base necessary to abstract the proton is a tertiary alkoxide that is generated from the hydroquinone form of vitamin K, through a mechanism involving the reaction with molecular oxygen, referred to as base strength amplification by oxidation [206]

Sheppard MC, Kronheim S, Pimstone BL

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demonstrated that pitavastatin can inhibit LC cells and angiogenesis, which was achieved by the induction of apoptosis and inhibition of proliferation of LC cells and human lung tumor-associated endothelial cells