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While iMAT, INIT, and mCADRE are switch approaches in which reactions are turned on/off depending on gene expression levels, E-flux is a valve approach in which each reaction is constrained based on the gene expression values

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10.2217/fon.16.3 Future Oncol

doi: .0000230499.07273.c5

(Bottom) Coomassie-stained SDS-PAGE of individual fractions from major peaks
