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Countering Changes in Time Cues The accumulated knowledge on the deleterious effects of abruptly changing time cues in for example shift work and jet lag [e.g., (6167)] lead to the suggestion that one function of endogenous melatonin is to protect against abrupt short term changes of phase by maintenance of the circadian status quo

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A systematic search was performed across multiple English-language scientific databases, including PubMed, Scopus, Web of Science, and Google Scholar, ensuring access to a broad range of biomedical, clinical, and interdisciplinary studies