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Although the exact mechanism of ADE remains to be understood, ADE has been reported to take place in two possible ways, first, internalization of virusantibody immune complexes into phagocytic cells via interaction of the antibody Fc region with the cellular Fc receptors present on myeloid cells which then render immune system to trigger signal transduction, releasing inflammatory cytokines, superoxide burst, and antibody-dependent cell-mediated cytotoxicity (ADCC) leading to the heightened antibody-mediated uptake of the virus 27,38,55 (Fig

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Within 2 to 4 weeks, these men experience severe acne (affecting 60 percent of TRT users), irritability, fluid retention, elevated blood pressure, or sleep disruption

Liu WJ, Ye L, Huang WF, Guo LJ, Xu ZG, Wu HL, Yang C, Liu HF

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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Autoimmune gastritis results in disruption of gastric epithelial cell development