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The Nrf2 protein then translocates into the cell nucleus, where it binds to the Antioxidant Response Element (ARE) on the DNA

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Nagayama Y (2018) Radiation-related thyroid autoimmunity and dysfunction

Nicotinamide adenine dinucleotide phosphate hydrogen (NADH) and flavin adenine dinucleotide (FADH2) begin the chain by donating their electrons to complex I and complex II, respectively

We purchased the following antibodies from Cell Signaling Technology (Beverly, MA): anti-phospho-ERK1/2 (T202/Y204) (1:1000, 9106)